http://repositorio.unb.br/handle/10482/26149
Arquivo | Tamanho | Formato | |
---|---|---|---|
v99n8a19.pdf | 23,2 kB | Adobe PDF | Visualizar/Abrir |
Título: | Hepatitis C virus genotypes in blood donors from the Federal District, Central Brazil |
Autor(es): | Amorim, Regina MS Oliveira, Claudiner P Wyant, Patrícia S Cerqueira, Daniela M Câmara, Geni NL Flores, Luciano S Martins, Regina MB Martins, Cláudia RF |
Assunto: | Hepatite C Genótipos |
Data de publicação: | 2004 |
Editora: | Instituto Oswaldo Cruz, Ministério da Saúde |
Referência: | Mem. Inst. Oswaldo Cruz,v.99,n.8,p.895-897,2004 |
Resumo: | The objective of this study was to characterize hepatitis C virus (HCV) genotypes in blood donors from the Federal District, Central Brazil, and to compare HCV screening by serological assays and reverse transcriptase polymerase chain reaction (RT-PCR). Plasma samples from 57 individuals with reactive or indeterminate results in serological anti-HCV screening assays (ELISA or EIA) were tested for HCV RNA by RT-PCR. The results from a confirmatory LIA serological assay were also evaluated. The 5' non-coding region of the HCV genome was amplified from 41 PCR positive samples (71.9%), which were further characterized by nucleotide sequencing analysis. Of these, 60.9% were of HCV genotype 1 and 39.1% of genotype 3. |
Unidade Acadêmica: | Em processamento |
DOI: | https://dx.doi.org/10.1590/S0074-02762004000800019 |
Aparece nas coleções: | Artigos publicados em periódicos e afins |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.