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dc.contributor.authorParize, Alexandre Luispt_BR
dc.contributor.authorStulzer, Hellen Karinept_BR
dc.contributor.authorLaranjeira, Mauro César Marghettipt_BR
dc.contributor.authorBrighente, Inês Maria da Costapt_BR
dc.contributor.authorSouza, Tereza Cristina Rozone dept_BR
dc.date.accessioned2017-12-07T04:58:41Z-
dc.date.available2017-12-07T04:58:41Z-
dc.date.issued2012pt_BR
dc.identifier.citationPARIZE, Alexandre Luis et al. Evaluation of chitosan microparticles containing curcumin and crosslinked with sodium tripolyphosphate produced by spray drying. Química Nova, São Paulo, v. 35, n. 6, p. 1127-1132, 2012. DOI: https://doi.org/10.1590/S0100-40422012000600011. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600011&lng=en&nrm=iso&tlng=en. Acesso em: 22 out. 2020.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/28331-
dc.language.isoenpt_BR
dc.publisherSociedade Brasileira de Químicapt_BR
dc.rightsAcesso Abertopt_BR
dc.titleEvaluation of chitosan microparticles containing curcumin and crosslinked with sodium tripolyphosphate produced by spray dryingpt_BR
dc.typeArtigopt_BR
dc.subject.keywordQuitosanapt_BR
dc.subject.keywordCurcuminapt_BR
dc.subject.keywordSecagempt_BR
dc.rights.licenseQuímica Nova - (CC BY-NC) - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422012000600011&lng=en&nrm=iso&tlng=en. Acesso em: 22 out. 2020.-
dc.identifier.doihttps://dx.doi.org/10.1590/S0100-40422012000600011pt_BR
dc.description.abstract1The aim of this study was to encapsulate curcumin into chitosan, using sodium tripolyphosphate (TPP) as an ionic crosslinker by the spray drying method. The influence of TPP on the properties of the final product, such as solubility, morphology, loading efficiency, thermal behavior, swelling degree and release profiles, was evaluated. The microparticles had a spherical morphology (0.5-20 µm) with no apparent porosity or cracks. Results indicated the formation of a polymeric network, which ensures effective protection for curcumin. Controlled-release studies were carried out at pH 1.2 and 6.8, to observe the influence of pH on curcumin release while the mechanism was analyzed using the Korsmeyer-Peppas equation.-
dc.description.unidadeInstituto de Química (IQ)pt_BR
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