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dc.contributor.authorDurães, Leonardo de Castropt_BR
dc.contributor.authorFarias, Igor Eduardo Caetano dept_BR
dc.contributor.authorMorais, Pedro Henrique Alves dept_BR
dc.contributor.authorOliveira, Paulo Gonçalves dept_BR
dc.contributor.authorCavalcanti Neto, Florêncio Figueiredopt_BR
dc.contributor.authorLino Junior, Ruy de Souzapt_BR
dc.contributor.authorFeres, Omarpt_BR
dc.contributor.authorSousa, João Batista dept_BR
dc.date.accessioned2017-12-07T05:02:47Z-
dc.date.available2017-12-07T05:02:47Z-
dc.date.issued2013pt_BR
dc.identifier.citationDURÃES, Leonardo de Castro et al. The effect of carbon dioxide pneumoperitoneum on the healing colonic anastomosis in rats. Acta Cirúrgica Brasileira, v. 28, n. 9, p. 670-677, 2013. DOI: https://doi.org/10.1590/S0102-86502013000900008. Disponível em: https://www.scielo.br/j/acb/a/d9SjmqRrTzFTFxFLGWR5Vhc/?lang=en#. Acesso em: 10 jul. 2021.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/28805-
dc.language.isoenpt_BR
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgiapt_BR
dc.rightsAcesso Abertopt_BR
dc.titleThe effect of carbon dioxide pneumoperitoneum on the healing colonic anastomosis in ratspt_BR
dc.typeArtigopt_BR
dc.subject.keywordPneumoperitôniopt_BR
dc.subject.keywordDióxido de carbonopt_BR
dc.subject.keywordAnastomosept_BR
dc.subject.keywordCicatrização de feridaspt_BR
dc.subject.keywordCólon (Anatomia) - cirurgiapt_BR
dc.subject.keywordRatospt_BR
dc.rights.licenseActa Cirúrgica Brasileira - This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY NC). Fonte: https://www.scielo.br/j/acb/a/d9SjmqRrTzFTFxFLGWR5Vhc/?lang=en#. Acesso em: 10 jul. 2021.-
dc.identifier.doihttps://dx.doi.org/10.1590/S0102-86502013000900008pt_BR
dc.description.abstract1PURPOSE: To investigate the effects of pneumoperitoneum on colonic anastomosis healing. METHODS: Colonic anastomosis was performed in 120 rats divided into four groups: Group I - pneumoperitoneum before laparotomy, Group II - pneumoperitoneum after laparorrhaphy, Group III - pneumoperitoneum before laparotomy and after laparorrhaphy, Group IV - no pneumoperitoneum (control group). Pneumoperitoneum pressure was 5 mmHg. Animals were killed on the 3rd, 7th and 14th postoperative day. Hhistopathological features, anastomosis breaking strength, collagen histomorphometry and hydroxyproline concentration were assessed. RESULTS: Breaking strength between groups: (day 3, p=0.165; day 7, p=0.219; day 14, p=0.539). Histopathology revealed that group II had, on day 7, less infiltration of mononuclear cells (p=0.006), greater infiltration of polymorphonuclear cells (p=0.001) and greater necrosis (p=0.001); and on day 14, less fibrosis. Histomorphometry revealed a decrease in collagen in groups I and III (p<0.001) on day 7 and an increase in groups I and II on day 14 (p<0.001). Hydroxyproline concentration was similar for groups on days 3 (p=0.152), 7 (p=0.913) or 14 (p=0.981). CONCLUSION: Carbon dioxide does not impair the healing of colonic anastomosis in rats.-
dc.description.unidadeFaculdade de Medicina (FMD)-
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