| Campo DC | Valor | Idioma |
|---|
| dc.contributor.author | Santarem, Ana Angélica Amorim | pt_BR |
| dc.contributor.author | Greggianin, Gabriel Frizon | pt_BR |
| dc.contributor.author | Debastiani, Rafaela Garcia | pt_BR |
| dc.contributor.author | Ribeiro, Jefferson Bruno Pereira | pt_BR |
| dc.contributor.author | Polli, Démerson André | pt_BR |
| dc.contributor.author | Sampaio, Raimunda Nonata Ribeiro | pt_BR |
| dc.date.accessioned | 2017-12-07T05:05:26Z | - |
| dc.date.available | 2017-12-07T05:05:26Z | - |
| dc.date.issued | 2014-08 | pt_BR |
| dc.identifier.citation | SANTAREM, Ana Angélica Amorim et al. Effectiveness of miltefosine-pentoxifylline compared to miltefosine in the treatment of cutaneous leishmaniasis in C57Bl / 6 mice. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 47, n. 4, p. 517-520, jul./ago. 2014. DOI: https://doi.org/10.1590/0037-8682-0202-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400517&lng=en&tlng=en. Acesso em: 27 jul. 2020. | pt_BR |
| dc.identifier.uri | http://repositorio.unb.br/handle/10482/29126 | - |
| dc.language.iso | en | pt_BR |
| dc.publisher | Sociedade Brasileira de Medicina Tropical - SBMT | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Effectiveness of miltefosine-pentoxifylline compared to miltefosine in the treatment of cutaneous leishmaniasis in C57Bl / 6 mice | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Leishmaniose cutânea | pt_BR |
| dc.subject.keyword | Pentoxifilina | pt_BR |
| dc.subject.keyword | Miltefosina | pt_BR |
| dc.rights.license | Revista da Sociedade Brasileira de Medicina Tropical - (CC BY-NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000400517&lng=en&tln g=en. Acesso em: 27 jul. 2020. | - |
| dc.identifier.doi | https://dx.doi.org/10.1590/0037-8682-0202-2013 | pt_BR |
| dc.description.abstract1 | Introduction The treatment of leishmaniasis ischallenging, given the difficulties in drug administration and resistance. Therefore, we chose to test the efficacy of miltefosine combined with pentoxifylline. Methods Twenty-seven isogenic C57Bl/6 mice were infected with Leishmania (Leishmania) amazonensis, and equally divided into three groups: miltefosine (200mg/kg/day), miltefosine (200mg/kg/day) with pentoxifylline (8mg/kg/day), and untreated. Response to treatment was evaluated using paw diameter and parasitological criteria. Results The number of viable Leishmania reduced significantly within the miltefosine-pentoxifylline group (p < 0.05). Conclusions There is hope that a viable treatment exists for Leishmania infection. | - |
| dc.description.unidade | Faculdade de Medicina (FMD) | - |
| Aparece nas coleções: | Artigos publicados em periódicos e afins
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