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dc.contributor.authorAlvim, Haline Gerica de Oliveirapt_BR
dc.contributor.authorCorrêa, José Raimundopt_BR
dc.contributor.authorMachado, Taynara Rezendept_BR
dc.contributor.authorSilva, Wender Alves dapt_BR
dc.contributor.authorNeto, Brenno A.pt_BR
dc.date.accessioned2017-12-07T05:07:07Z-
dc.date.available2017-12-07T05:07:07Z-
dc.date.issued2014pt_BR
dc.identifier.citationALVIM, Haline Gerica de Oliveira et al. Catalyzed and non-catalyzed synthesis of bioactive monastrol. Química Nova, São Paulo, v. 37, n. 10, p. 1713-1715, 2014. DOI: http://dx.doi.org/10.5935/0100-4042.20140266. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000022&lng=en&nrm=iso&tlng=en. Acesso em: 20 jul. 2020.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/29152-
dc.language.isoenpt_BR
dc.publisherSociedade Brasileira de Químicapt_BR
dc.rightsAcesso Abertopt_BR
dc.titleCatalyzed and non-catalyzed synthesis of bioactive monastrolpt_BR
dc.typeArtigopt_BR
dc.subject.keywordMonastrolpt_BR
dc.subject.keywordReação de Biginellipt_BR
dc.subject.keywordCatálisept_BR
dc.rights.licenseQuímica Nova - (CC BY-NC) - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422014001000022&lng=en&nr m=iso&tlng=en. Acesso em: 20 jul. 2020.-
dc.identifier.doihttps://dx.doi.org/10.5935/0100-4042.20140266pt_BR
dc.description.abstract1The bioactive 3,4-dihydropyrimidin-2(1H)-thione derivative known as Monastrol was synthesized under catalyzed and non-catalyzed conditions through the Biginelli multicomponent reaction under solvent-free conditions. The use of two Lewis acids (FeCl3 and CuCl2) and two Brønsted acids (HCl and CF3COOH) as catalysts improved the reaction yields of the transformation compared with the non-catalyzed reaction. The experiments investigated catalysis and its role, the importance of multicomponent reactions and their green features, and the application of these concepts to the synthesis of a biologically important structure.-
dc.description.unidadeInstituto de Química (IQ)pt_BR
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