| Campo DC | Valor | Idioma |
|---|
| dc.contributor.author | Paula, Roberta S. | pt_BR |
| dc.contributor.author | Souza, Vinícius C. | pt_BR |
| dc.contributor.author | Machado-Silva, Wilcelly | pt_BR |
| dc.contributor.author | Almeida, Bruno Ratier S. | pt_BR |
| dc.contributor.author | Daros, Andersen C. | pt_BR |
| dc.contributor.author | Gomes, Lucy | pt_BR |
| dc.contributor.author | Ferreira, Aparecido P. | pt_BR |
| dc.contributor.author | Brito, Ciro J. | pt_BR |
| dc.contributor.author | Córdova, Cláudio | pt_BR |
| dc.contributor.author | Moraes, Clayton F. | pt_BR |
| dc.contributor.author | Nóbrega, Otávio T. | pt_BR |
| dc.date.accessioned | 2017-12-07T05:18:55Z | - |
| dc.date.available | 2017-12-07T05:18:55Z | - |
| dc.date.issued | 2016-12 | pt_BR |
| dc.identifier.citation | PAULA, Roberta S. et al. Serum Klotho (but not haplotypes) associate with the post-myocardial infarction status of older adults. Clinics, São Paulo, v. 71, n. 12, p. 725-732, dez. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322016001200725&lng=en&nrm=iso>. Acesso em: 18 dez. 2017. doi: http://dx.doi.org/10.6061/clinics/2016(12)09. | pt_BR |
| dc.identifier.uri | http://repositorio.unb.br/handle/10482/30394 | - |
| dc.language.iso | en | pt_BR |
| dc.publisher | Faculdade de Medicina / USP | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Serum Klotho (but not haplotypes) associate with the post-myocardial infarction status of older adults | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | Biomarcadores | pt_BR |
| dc.subject.keyword | Idosos | pt_BR |
| dc.subject.keyword | Infarto | pt_BR |
| dc.rights.license | Clinics - This is an Open Access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited (CC BY 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322016001200725&lng=en&nrm=iso. Acesso em: 18 dez. 2017. | - |
| dc.identifier.doi | http://dx.doi.org/10.6061/clinics/2016(12)09 | pt_BR |
| dc.description.abstract1 | The number of deaths from vascular diseases is incredibly high worldwide, and reliable markers for major events are still needed. The current cross-sectional study investigated the association of Klotho haplotypes and Klotho serum levels with classic risk factors and a clinical history of vascular events. METHODS: Clinical, anthropometric, biochemical and nutritional assessments were conducted with 168 older adults, complemented by genotyping (rs9536314 and rs9527025) and the detection of serum Klotho (ELISA). RESULTS: Klotho levels and haplotypes did not associate with most classic risk factors for vascular events, including markers such as C-reactive protein and homocysteine. A positive association was only found between Klotho levels and the previous occurrence of a myocardial infarction by both correlational (p=0.006) and variance analyses (p<0.001), and these associations were independent of the context. CONCLUSION: Our results suggest that serum Klotho is higher in individuals with a clinical history of myocardial infarction but not with a history of coronary artery disease or stroke. None of the Klotho haplotypes were associated with the variables investigated herein. | - |
| Aparece nas coleções: | Artigos publicados em periódicos e afins
|
