Campo DC | Valor | Idioma |
dc.contributor.author | Gomes, Lorena Ferreira | - |
dc.contributor.author | Martins, Diegue Henrique Nascimento | - |
dc.contributor.author | Silva, Sandra Marcia Mazutti da | - |
dc.contributor.author | Barros, Yuri Yabu de | - |
dc.contributor.author | Souza, Paula Monteiro de | - |
dc.contributor.author | Freitas, Marcela Medeiros de | - |
dc.contributor.author | Fagg, Christopher William | - |
dc.contributor.author | Simeoni, Luiz Alberto | - |
dc.contributor.author | Batista, Pérola de Oliveira Magalhães Dias | - |
dc.contributor.author | Silveira, Dâmaris | - |
dc.contributor.author | Fonseca-Bazzo, Yris Maria | - |
dc.date.accessioned | 2021-06-17T18:24:20Z | - |
dc.date.available | 2021-06-17T18:24:20Z | - |
dc.date.issued | 2021-03-22 | - |
dc.identifier.citation | GOMES, Lorena Ferreira et al. Propiedades biológicas y caracterización fitoquímica del extracto acuoso de Miconia chamissois Naudin. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas, v. 20, n. 4, p. 427-442, jul. 2021. DOI: https://doi.org/10.37360/blacpma.21.20.4.32. Disponível em: https://blacpma.ms-editions.cl/index.php/blacpma/article/view/181. Acesso em: 17 jun. 2021. | pt_BR |
dc.identifier.uri | https://repositorio.unb.br/handle/10482/41192 | - |
dc.language.iso | Inglês | pt_BR |
dc.publisher | MS-Editions | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.title | Biological properties and phytochemical characterization from Miconia chamissois Naudin aqueous extract | pt_BR |
dc.title.alternative | Propiedades biológicas y caracterización fitoquímica del extracto acuoso de Miconia chamissois Naudin | pt_BR |
dc.type | Artigo | pt_BR |
dc.subject.keyword | Antioxidantes | pt_BR |
dc.subject.keyword | Agentes antiinfecciosos | pt_BR |
dc.subject.keyword | Polifenóis | pt_BR |
dc.subject.keyword | Tirosinase | pt_BR |
dc.subject.keyword | α-amilase | pt_BR |
dc.subject.keyword | Miconia chamissois | pt_BR |
dc.rights.license | (CC BY NC ND) Este trabalho está sob uma licença internacional Creative Commons Attribution-NonCommercial-NoDerivatives 4.0. Fonte: https://blacpma.ms-editions.cl/index.php/blacpma/article/view/181. Acesso em: 17 jun. 2021. | pt_BR |
dc.identifier.doi | https://doi.org/10.37360/blacpma.21.20.4.32 | pt_BR |
dc.description.abstract1 | The objective of this study was to evaluate biological and phytochemical properties of the aqueous extract from the leaves of Miconia chamissoisNaudin (AEMC). Phytochemical properties were assessed by analyzing the chromatographic profile and the polyphenol content of AEMC. Biological properties evaluation wasconducted based on cytotoxicity assay and by evaluating the antioxidant, antimicrobial, and enzymatic inhibition activities. Results indicated the presence of phytochemicals in AEMC such as flavonoids and polyphenols, including rutin, isoquercitrin and vitexin derivatives. AEMC showed antioxidant activity, which may be attributed to the high polyphenolic content. Moreover, AEMC demonstrated in vitro enzyme inhibition activity against tyrosinase and alpha-amylase, as well as showed low cytotoxicity. On the other hand, AEMC exhibited weak antimicrobial activity against S. aureusand C. albicans. Thus, AEMC is a promising alternative in search of potential drugs for the treatment of diseases induced by oxidative stress and inflammation, conditions due to hyperpigmentation processes, such as melisma, as well as for diabetes. | pt_BR |
dc.description.abstract2 | El objetivo de este estudio fue detectar las propiedades biológicas y fitoquímicos del extracto acuoso de las hojas de Miconia chamissois Naudin (AEMC). Las propiedades fitoquímicas se evaluaron analizando el perfil cromatográfico y el contenido de polifenoles de AEMC. La evaluación de las propiedades biológicas se realizó en base al ensayo de citotoxicidad y evaluando las actividades de inhibición antioxidante, antimicrobiana y enzimática. Los resultados indicaron la presencia de fitoquímicos en AEMC, como flavonoides y polifenoles, que incluyen derivados de rutina, isoquercitrina y vitexina. AEMC mostró una actividad antioxidante considerable, que puede atribuirse al alto contenido polifenólico. Además, AEMC exhibió actividad de inhibición enzimática in vitro contra tirosinasa y alfa-amilasa, así como mostró baja citotoxicidad. Por otro lado, AEMC demostró actividad antimicrobiana débil contra S. aureus y C. albicans. Por lo tanto, AEMC es una alternativa prometedora en busca de posibles drogas para el tratamiento de enfermedades inducidas por el estrés oxidativo y la inflamación, afecciones debidas a procesos de hiperpigmentación, como el melasma, así como para la diabetes. | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-4917-199X | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-3879-5895 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-7398-7908 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-9502-1071 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0003-1824-2211 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-6112-9903 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-6072-7832 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0003-3401-290X | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-8011-6940 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0003-1851-5224 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-1230-3207 | pt_BR |
Aparece nas coleções: | Artigos publicados em periódicos e afins
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