Título:	Deconstruction of lignin : from enzymes to microorganisms
Autor(es):	Silva, Jéssica P. Ticona, Alonso R. P. Hamann, Pedro Ricardo Vieira Quirino, Betania F. Noronha, Eliane Ferreira
ORCID:	https://orcid.org/0000-0002-9027-1589 https://orcid.org/0000-0002-7578-6314
Assunto:	Lignina Bactérias Biodegradação Metagenômica Metaproteômica Metatranscriptomia
Data de publicação:	15-Abr-2021
Editora:	MDPI
Referência:	SILVA, Jéssica P. et al. Deconstruction of lignin: from enzymes to microorganisms. Molecules, v. 26, n. 8, 2299, 2021. DOI: https://doi.org/10.3390/molecules26082299. Disponível em: https://www.mdpi.com/1420-3049/26/8/2299. Acesso em: 22 ago. 2022.
Abstract:	Lignocellulosic residues are low-cost abundant feedstocks that can be used for industrial applications. However, their recalcitrance currently makes lignocellulose use limited. In natural environments, microbial communities can completely deconstruct lignocellulose by synergistic action of a set of enzymes and proteins. Microbial degradation of lignin by fungi, important lignin degraders in nature, has been intensively studied. More recently, bacteria have also been described as able to break down lignin, and to have a central role in recycling this plant polymer. Nevertheless, bacterial deconstruction of lignin has not been fully elucidated yet. Direct analysis of environmental samples using metagenomics, metatranscriptomics, and metaproteomics approaches is a powerful strategy to describe/discover enzymes, metabolic pathways, and microorganisms involved in lignin breakdown. Indeed, the use of these complementary techniques leads to a better understanding of the composition, function, and dynamics of microbial communities involved in lignin deconstruction. We focus on omics approaches and their contribution to the discovery of new enzymes and reactions that impact the development of lignin-based bioprocesses.
Licença:	Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
DOI:	https://doi.org/10.3390/molecules26082299
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