Dental pulp and apical papilla cells senescence : causes,  consequences, and prevention

Farias, Jade Ormondes de; Rezende, Taia Maria Berto

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Campo DC	Valor	Idioma
dc.contributor.author	Farias, Jade Ormondes de	-
dc.contributor.author	Rezende, Taia Maria Berto	-
dc.date.accessioned	2024-06-07T15:37:15Z	-
dc.date.available	2024-06-07T15:37:15Z	-
dc.date.issued	2023	-
dc.identifier.citation	FARIAS, Jade Ormondes de; REZENDE, Taia Maria Berto. Dental pulp and apical papilla cells senescence: causes, consequences, and prevention. Biogerontology, [S. l.], v. 24, p. 533–539, 2023. DOI: https://doi.org/10.1007/s10522-023-10029-y.	pt_BR
dc.identifier.uri	http://repositorio2.unb.br/jspui/handle/10482/48175	-
dc.language.iso	eng	pt_BR
dc.publisher	Springer Nature B.V	pt_BR
dc.rights	Acesso Restrito	pt_BR
dc.title	Dental pulp and apical papilla cells senescence : causes, consequences, and prevention	pt_BR
dc.type	Artigo	pt_BR
dc.subject.keyword	Senescência celular	pt_BR
dc.subject.keyword	Polpa dentária	pt_BR
dc.subject.keyword	Papila apical	pt_BR
dc.identifier.doi	https://doi.org/10.1007/s10522-023-10029-y	pt_BR
dc.relation.publisherversion	https://link.springer.com/article/10.1007/s10522-023-10029-y	pt_BR
dc.description.abstract1	Dental pulp under physiological condi tions has a defense function, repair capacity, and important mechanisms in pathological processes. In addition, the dental papilla is involved in important defense processes and an essential function in the pulp revascularization process. It is known that dental pulp and apical papilla undergo a natural aging process, in addition to stressful situations such as bruxism, infammation, and infections. Both aging and stressful situations can lead to cellular senescence. Some evidence indicates that the changes resulting from this cellular state can directly afect the ef ciency of cells in these tissues and afect conservative and regenerative clinical treatments. Thus, it is nec essary to understand the causes and consequences o cellular senescence in addition to the development of methods for senescence prevention. This review aims to provide an overview of possible causes and conse quences of senescence in dental pulp and stem cells from apical papilla and discusses possible methods to prevent this cellular state.	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0001-9347-3330	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0002-4148-0659	pt_BR
dc.contributor.affiliation	Universidade de Brasília, Faculdade de Ciências de Saúde, Pós-graduação em Ciências da Saúde	pt_BR
dc.contributor.affiliation	Universidade de Brasília, Faculdade de Ciências de Saúde, Pós-graduação em Ciências da Saúde	pt_BR
dc.contributor.affiliation	Universidade Católica de Brasília, Curso de Odontologia	pt_BR
dc.contributor.affiliation	Universidade Católica de Brasília, Pós-graduação em Ciências Genômicas e Biotecnologia	pt_BR
dc.description.unidade	Faculdade de Ciências da Saúde (FS)	pt_BR
dc.description.unidade	Departamento de Odontologia (FS ODT)	pt_BR
dc.description.ppg	Programa de Pós-Graduação em Ciências da Saúde	pt_BR
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