Title:	Glicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de Solanum asperum
Other Titles:	Antifungal glycoalkaloids, flavonoids and other chemical constituents of Solanum asperum Rich (Solanaceae)
Authors:	Pinto, Francisco das Chagas L. Uchoa, Daniel Esdras de Andrade Silveira, Edilberto Rocha Pessoa, Otília Deusdênia Loiola Braz-Filho, Raimundo Silva, Fernanda Melo e Theodoro, Phellipe Norato Estrela Terra Espindola, Laila Salmen
Assunto::	Solanum asperum Antimicóticos Plantas - compostos bioativos
Issue Date:	2011
Publisher:	Sociedade Brasileira de Química
Citation:	PINTO, Francisco das Chagas L. et al. Glicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de Solanum asperum. Química Nova, São Paulo, v. 34, n. 2, 2011. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000200021&lng=pt&nrm=iso&tlng=pt>. Acesso em: 6 jun. 2013.
Abstract:	Two glycoalkaloids: solamargine and solasonine; three flavonoids: tiliroside, 7-O-α-L-ramnopyranosyl-kaempferol and 3-O-[ß-D-glucopyranosyl-(1→6)-α-L-ramnopyranosyl]-7- O-α-L-ramnopyranosyl-kaempferol, in addition to the tripeptide Leu-Ile-Val, the aminoacid proline and the eicosanoic acid were isolated from Solanum asperum (Solanaceae). The structures of all compounds were determined by interpretation of their spectra (IR, MS, 1H and 13C NMR) and comparison with the literature data. All compounds, except the glycoalkaloids, are being reported for the first time for S. asperum. Solasonine showed strong activity (MIC < 0.24 μg/mL) against four filamentous fungi species of the genera Microsporum and Trichophyton.
Licença::	Química Nova - Todo o conteúdo deste periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0)). Fonte: http://www.scielo.br/scielo.php?script=sci_serial&pid=0100-4042&lng=pt&nrm=iso. Acesso em: 6 jun. 2013.
DOI:	http://dx.doi.org/10.1590/S0100-40422011000200021
Appears in Collections:	Artigos publicados em periódicos e afins

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