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Titre: Neurodevelopment of amazonian infants : antenatal and postnatal exposure to methyl- and ethylmercury
Auteur(s): Dórea, José Garrofe
Marques, Rejane Corrêa
Isejima, Cintya Kazumi
Assunto:: Mercúrio - toxicologia
Saúde infantil
Neurotoxicidade
Desenvolvimento da criança
Sistema nervoso central
Peixe - alimento
Date de publication: 2012
Editeur: BioMed Research International
Référence bibliographique: DÓREA, José G.; MARQUES, Rejane C.; ISEJIMA, Cintya. Neurodevelopment of amazonian infants: antenatal and postnatal exposure to methyl- and ethylmercury. Journal of Biomedicine and Biotechnology, v. 2012, 2012. Disponível em: <http://www.hindawi.com/journals/bmri/2012/132876/>. Acesso em: 5 jul. 2013. DOI: 10.1155/2012/132876.
Résumé: Neurodevelopment as Gesell development scores (GDSs) in relation to mercury exposure in infants (<6 months of age) of one urban center and two rural villages, respectively, of fisherman and cassiterite miners. Mean total hair-Hg (HHg) concentrations of infants from Itapua (3.95 ± 1.8 ppm) were statistically (P = 0.0001) different from those of infants from Porto Velho (3.84 ± 5.5 ppm) and Bom Futuro (1.85 ± 0.9 ppm). Differences in vaccine coverage among these populations resulted in significantly higher (P = 0.0001) mean ethylmercury (EtHg) exposure in urban infants (150 μg) than in infants from either village (41.67 μg, Itapua; 42.39 μg, Bom Futuro). There was an inverse significant (Spearman r = −0.2300; P = 0.0376) correlation between HHg and GDS for infants from Porto Velho, but not for the rural infants from Bom Futuro (Spearman r = 0.1336; P = 0.0862) and Itapua (Spearman r = 0.1666; P = 0.5182). Logistic regression applied to variables above or below the median GDS showed that EtHg exposure (estimated probability = −0.0157; P = 0.0070) and breastfeeding score (estimated probability = −0.0066; P = 0.0536) score were significantly associated with GDS.Conclusion. In nurslings whose mothers are exposed to different levels of fish-MeHg (HHg), a higher score of neurological development at six months was negatively associated with exposure to additional TCV-EtHg. Results should be interpreted with caution because of unaccounted variables.
Licença:: Copyright © 2012 José G. Dórea et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: http://www.hindawi.com/journals/bmri/2012/132876/. Acesso em: 5 jul. 2013.
DOI: https://dx.doi.org/10.1155/2012/132876
Collection(s) :Artigos publicados em periódicos e afins

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