http://repositorio.unb.br/handle/10482/26297| File | Size | Format | |
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| ARTIGO_HLABrazilianAshkenazic.pdf | 91,08 kB | Adobe PDF | View/Open |
| Title: | HLA in Brazilian Ashkenazic jews with chronic dermatophytosis caused by Trichophyton rubrum |
| Other Titles: | Antígenos Leucocitários Humanos (HLA) em judeus Ashkenazitas brasileiros portadores de dermatofitose crônica causada por Trichophyton rubrum |
| Authors: | Sadahiro, Aya Moraes, José Roberto Feresin Moraes, Maria Elisa Hue Romero, Matilde Gouvea, Nancy Alves de Lima Gouvea, Celso José Ogusku, Mauricio Morishi Campbell, Iphis Zaitz, Clarisse |
| Assunto:: | Trichophyton rubrum Antígenos de histocompatibilidade HLA |
| Issue Date: | 2004 |
| Publisher: | Sociedade Brasileira de Microbiologia |
| Citation: | SADAHIRO, Aya et al. HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum. Brazilian Journal of Microbiology, v. 35, n. 1-2, p. 69-73, 2004. DOI: https://doi.org/10.1590/S1517-83822004000100011. Disponível em: https://www.scielo.br/j/bjm/a/gG9TLNS8rTMMJvZSgbLnhYm/?lang=en#. Acesso em: 10 set. 2021. |
| Abstract: | A freqüência dos HLA foi analisada em 25 Judeus Ashkenazitas, não consangüíneos, residentes em São Paulo, Brasil, com dermatofitose crônica causada por T. rubrum e em 25 indivíduos sadios, pertencentes ao mesmo grupo étnico dos pacientes. Observou-se valor estatisticamente significante (p<0,05) para HLA-B14 associado a resistência à dermatofitose crônica enquanto HLA-DQB1*06 (p=0,05) possivelmente relacionado a susceptibilidade. Estes achados indicam que o desenvolvimento da dermatofitose crônica pode ser influenciado por genes localizados no cromossomo 6, na região do complexo principal de histocompatibilidade. |
| Abstract: | The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p<0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis. |
| metadata.dc.description.unidade: | Faculdade de Medicina (FMD) |
| Licença:: | Brazilian Journal of Microbiology - This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY NC). Fonte: https://www.scielo.br/j/bjm/a/gG9TLNS8rTMMJvZSgbLnhYm/?lang=en#. Acesso em: 10 set. 2021. |
| DOI: | https://dx.doi.org/10.1590/S1517-83822004000100011 |
| Appears in Collections: | Artigos publicados em periódicos e afins |
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