Title:	The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer : evidence-based medicine
Authors:	Novaes, Maria Rita Carvalho Garbi Valadares, Fabiana Peçanha Reis, Mariana Campos Gonçalves, Daniella Rodrigues Menezes, Marilia da Cunha
Assunto::	Suplementação nutricional Agaricus sylvaticus Cogumelos Tratamento Basidiomicetos
Issue Date:	2011
Publisher:	Faculdade de Medicina / USP
Citation:	NOVAES, Maria Rita Carvalho Garbi et al. The effects of dietary supplementation with Agaricales mushrooms and other medicinal fungi on breast cancer: evidence-based medicine. Clinics, v. 66, n. 12, p. 2133-2139, 2011. DOI: https://doi.org/10.1590/S1807-59322011001200021. Disponível em: https://www.scielo.br/j/clin/a/dFXsBY3HNSYNK5hFkv93BJs/?lang=en#. Acesso em: 10 ago. 2021.
Abstract:	Breast cancer is the most prevalent cancer in women. The most frequent therapeutic approaches for the treatment of this disease are chemotherapy, radiotherapy, hormone therapy, and surgery. Conventional pharmacological treatments cause many harmful side effects in patients. To improve the quality of life of breast cancer patients, researchers have sought alternative adjuvant treatment strategies. To assess the effects of fungi and other basidiomycetes Agaricales on the co-adjuvant treatment of breast cancer, we conducted a literary review of the available scientific evidence. We selected articles published in refereed journals from 1990 to 2011 in Medline, Lilacs, CAPES, Scielo, and Pubmed. Articles written in English, Spanish, and Portuguese were reviewed. We used the following descriptors: Agaricales, medicinal mushroom/fungus, breast cancer, dietary supplementation, synonyms, and related terms. The pharmacological effects of nutritional and medicinal mushrooms have been reported in several experimental clinical studies and have shown promising results in the adjuvant treatment of breast cancer. Adjuvant treatment with mushrooms is associated with improvements in the immunological and hematologic parameters of breast cancer, as well as in the quality of life of these patients. Randomized clinical studies are needed to elucidate the possible mechanisms of action and clinical benefits of these fungi with respect to survival time, disease progression, and metastasis in breast cancer.
Licença::	Copyright © 2011 CLINICS – This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOI:	https://dx.doi.org/10.1590/S1807-59322011001200021
Appears in Collections:	Artigos publicados em periódicos e afins

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