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dc.contributor.authorGonçalves, Heitor de Sápt_BR
dc.contributor.authorPontes, Maria Araci de Andradept_BR
dc.contributor.authorBührer-Sékula, Samirapt_BR
dc.contributor.authorCruz, Rossilenept_BR
dc.contributor.authorAlmeida, Paulo Cesarpt_BR
dc.contributor.authorMoraes, Maria Elisabete Amaral dept_BR
dc.contributor.authorPenna, Gerson Oliveirapt_BR
dc.date.accessioned2017-12-07T04:58:15Z-
dc.date.available2017-12-07T04:58:15Z-
dc.date.issued2012-12pt_BR
dc.identifier.citationGONÇALVES, Heitor de Sá et al. Brazilian clinical trial of uniform multidrug therapy for leprosy patients: the correlation between clinical disease types and adverse effects. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 107, supl. 1, p. 74-78, dez. 2012. DOI: https://doi.org/10.1590/S0074-02762012000900013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000900013&lng=en&tlng=en. Acesso em: 22 out. 2020.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/28309-
dc.language.isoenpt_BR
dc.publisherInstituto Oswaldo Cruz, Ministério da Saúdept_BR
dc.rightsAcesso Abertopt_BR
dc.titleBrazilian clinical trial of uniform multidrug therapy for leprosy patients : the correlation between clinical disease types and adverse effectspt_BR
dc.typeArtigopt_BR
dc.subject.keywordHanseníasept_BR
dc.subject.keywordEfeitos adversospt_BR
dc.subject.keywordTerapêuticapt_BR
dc.rights.licenseMemórias do Instituto Oswaldo Cruz - (CC BY-NC) - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000900013&lng=en&tlng=en. Acesso em: 22 out. 2020.-
dc.identifier.doihttps://dx.doi.org/10.1590/S0074-02762012000900013pt_BR
dc.description.abstract1This study sought to verify the correlation between leprosy types and the adverse effects of treatment drugs. This quantitative, prospective, nested study was developed at the Dona Libânia Dermatology Centre in Fortaleza, Brazil. Data were collected from November 2007-November 2008. During this period, 818 leprosy patients were diagnosed and began treatment. Forty patients with tuberculoid leprosy (TT) were selected. Twenty patients followed a standard therapy of dapsone and rifampicin and 20 were administered dapsone, rifampicin and clofazimine (U-MDT). Twenty patients with borderline lepromatous (BL) and lepromatous leprosy (LL) were also selected and treated with U-MDT. All of the subjects received six doses. With the exception of haemolytic anaemia, there was a low incidence of adverse effects in all the groups. We did not observe any differences in the incidence of haemolytic anaemia or other side effects across groups of patients with TT, BL or LL treated with U-MDT.-
dc.description.unidadeFaculdade de Medicina (FMD)-
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