Title:	Relationship between pre-sarcopenia, sarcopenia and bone mineral density in elderly men
Authors:	Pereira, Fernando Borges Leite, André Ferreira Paula, Ana Patrícia de
Assunto::	Sarcopenia Osteoporose Densidade mineral óssea Massa muscular Idosos
Issue Date:	Feb-2015
Publisher:	Sociedade Brasileira de Endocrinologia e Metabologia
Citation:	PEREIRA, Fernando Borges; LEITE, André Ferreira; PAULA, Ana Patrícia de. Relationship between pre-sarcopenia, sarcopenia and bone mineral density in elderly men. Archives of Endocrinology and Metabolism, São Paulo, v. 59, n. 1, p. 59-65, fev. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000100059&lng=en&nrm=iso>. Acesso em: 19 mar. 2018. doi: http://dx.doi.org/10.1590/2359-3997000000011.
Abstract:	Objective: analyze the influence of sarcopenia in bone health of elderly men. Subjects and methods: this cross-sectional study evaluated 198 men aged over 60 years. Body composition was measured by dual energy X-ray absorptiometry. The BMD was measured at the femoral neck, total hip, lumbar spine and 33% radius. The diagnosis of abnormal BMD was defined for men who presented densitometric diagnosis of osteopenia or osteoporosis defined by T-score of femoral neck, total hip and lumbar spine. The pre-sarcopenia and sarcopenia were defined according to the European Working Group on Sarcopenia in Older People. Results: the group diagnosed with normal BMD, compared to the group of abnormal BMD, have significantly higher body weight, body mass index, grip strength, lean mass, fat mass, and relative appendicular skeletal muscle mass (RASM). However, after multiple linear regression analysis, we found that only the RASM, lean mass, and handgrip strength in the dominant hand influenced the variability of the BMD after adjustment for age and weight. Regression analyzes showed a positive association between greater appendicular lean mass and a smaller number of elderly patients with abnormal BMD diagnostic. The regression analyzes showed that elderly men diagnosed with pre-sarcopenia and sarcopenia had more abnormal BMD than non-sarcopenic elderly men. Conclusion: we concluded that pre-sarcopenia and sarcopenia were associated with abnormal BMD. The lean mass, compared to fat mass, has a greater positive influence on the BMD of elderly men. This result suggests the importance of the increase in lean mass for the bone health of elderly men. Arch Endocrinol Metab. 2015;59(1):59-65
Licença::	Archives of Endocrinology and Metabolism - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY NC 3.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000100059&lng=en&nrm=iso. Acesso em: 19 mar. 2018.
DOI:	http://dx.doi.org/10.1590/2359-3997000000011
Appears in Collections:	Artigos publicados em periódicos e afins

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