Title:	A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism
Authors:	Vieira Neto, Leonardo Boguszewski, Cesar L. Araújo, Luiz Antônio de Bronstein, Marcello D. Miranda, Paulo Augusto Carvalho Musolino, Nina Rosa Castro Naves, Luciana Ansaneli Vilar, Lucio Oliveira Júnior, Antônio Ribeiro Gadelha, Mônica R.
Assunto::	Adenoma não-funcionante Radioterapia Fungos
Issue Date:	Aug-2016
Publisher:	Sociedade Brasileira de Endocrinologia e Metabologia
Citation:	VIEIRA NETO, Leonardo et al. A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism. Archives of Endocrinology and Metabolism, São Paulo, v. 60, n. 4, p. 374-390, ago. 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000400374&lng=en&nrm=iso>. Acesso em: 8 dez. 2017. doi: http://dx.doi.org/10.1590/2359-3997000000179.
Abstract:	Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and symptoms resulting from mass effect, such as neuro-ophthalmologic symptoms and hypopituitarism. Other presentations include pituitary apoplexy or an incidental finding on imaging studies. Mass effect and hypopituitarism impose high morbidity and mortality. However, early diagnosis and effective treatment minimizes morbidity and mortality. In this publication, the goal of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism is to provide a review of the diagnosis and treatment of patients with NFPA, emphasizing that the treatment should be performed in reference centers. This review is based on data published in the literature and the authors’ experience. Arch Endocrinol Metab. 2016;60(4):374-90
metadata.dc.description.unidade:	Faculdade de Medicina (FMD)
Licença::	Archives of Endocrinology and Metabolism - This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972016000400374&lng=en&nrm=iso. Acesso em: 8 dez. 2017.
DOI:	http://dx.doi.org/10.1590/2359-3997000000179
Appears in Collections:	Artigos publicados em periódicos e afins

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