Título :	Evaluation of the antimicrobial activity of silver nanoparticles obtained by microwave-assisted green synthesis using Handroanthus impetiginosus (Mart. ex DC.) Mattos underbark extract
Autor :	Illanes Tormena, Renata Pascoal Rosa, Eliane Vieira Mota, Bruna de Fatima Oliveira Chaker, Juliano Alexandre Fagg, Christopher William Freire, Daniel Oliveira Martins, Paula Melo Silva, Izabel Cristina Rodrigues da Sousa, Marcelo Henrique
metadata.dc.identifier.orcid:	https://orcid.org/0000-0003-3248-1286 https://orcid.org/0000-0002-2144-0959 https://orcid.org/0000-0001-6072-7832 https://orcid.org/0000-0003-1210-8329
metadata.dc.contributor.affiliation:	University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group Federal Institute of Education, Science and Technology Goiano, Ceres, GO University of Brasilia, Faculty of Ceilandia, Department of Pharmacy University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies LS Educational, Microbiology Laboratory, Brasilia, Brazil University of Brasilia, Faculty of Ceilandia, Department of Pharmacy University of Brasilia, Faculty of Ceilandia, Graduate Program in Health Sciences and Technologies University of Brasilia, Faculty of Ceilandia, Green Nanotechnology Group
Assunto::	Atividade antimicrobiana Nanopartículas de prata Ipê roxo
Fecha de publicación :	21-jun-2020
Editorial :	The Royal Society of Chemistry
Citación :	ILLANES TORMENA, Renata Pascoal et al. Evaluation of the antimicrobial activity of silver nanoparticles obtained by microwave-assisted green synthesis using Handroanthus impetiginosus (Mart. ex DC.) Mattos underbark extract. RSC Advances, [S. l.], v. 10, n. 35, 20676-20681, 2020. DOI: 10.1039/d0ra03240a. Disponível em: https://pubs.rsc.org/en/content/articlelanding/2020/RA/D0RA03240A. Acesso em: 28 nov. 2023.
Abstract:	We describe here a green method for the preparation of silver nanoparticles (AgNPs), by a microwave assisted synthesis route using Handroanthus impetiginosus underbark extract, with antibacterial activity. After optimizing the synthesis parameters with a Box–Benhken designed experiment, samples were characterized by powder XRD, TEM, UV-Vis spectroscopy, FTIR and zetametry. Using the overall optimized conditions of synthesis – time of reaction 15 min at 200 C and plant extract/AgNO3 volume ratio equal to 10% – highly crystalline 13.4 nm-sized spherical AgNPs in a well-dispersed colloidal state were obtained. It was also proved that the plant extract compounds act as reductant and capping agents during synthesis to functionalize AgNPs, resulting in a negatively charged surface with high values of zeta potential in a wide range of pH, from acidic to alkaline media. Biological activity tests against Staphylococcus aureus and Escherichia coli and cell viability experiments showed that synthesized AgNPs were not toxic to HaCaT mammalian cells and presented a high efficiency against Gram-positive bacteria (S. aureus). This was associated with the synergistic combination of AgNP silver cores with the capping layer containing natural compounds with antimicrobial properties and considered an alternative to the AgNPs commonly obtained from conventional routes that present antibacterial effectiveness preferentially against Gram-negative strains.
metadata.dc.description.unidade:	Faculdade UnB Ceilândia (FCE) Curso de Farmácia (FCE-FAR)
metadata.dc.description.ppg:	Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Licença::	(CC BY-NC). This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence
DOI:	https://doi.org/10.1039/D0RA03240A
Aparece en las colecciones:	Artigos publicados em periódicos e afins

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