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Titre: Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
Auteur(s): Yamashita, Hiromi
Zeredo, Jorge Luis Lopes
Toda, Kazuo
metadata.dc.identifier.orcid: https://orcid.org/0000-0002-2850-0731
https://orcid.org/0000-0003-0338-5850
https://orcid.org/0000-0002-8848-8017
metadata.dc.contributor.affiliation: Nagasaki University, Institute of Biomedical Sciences, Forensic Dental Science
University of Brasilia, Ceilandia Campus, Graduate Program in Health Science and Technolog
Nagasaki University, Institute of Biomedical Sciences, Integrative Sensory Physiology
Assunto:: Eletroacupuntura
Analgesia
Mandíbula
Date de publication: 31-aoû-2021
Editeur: Medical Association of Pharmacopuncture Institute
Référence bibliographique: YAMASHITA, Hiromi; ZEREDO, Jorge Luis Lopes; TODA, Kazuo. Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats. Journal of Acupuncture and Meridian Studies, [S.l.], v. 14, n. 4, 31 ago 2021. Disponível em: https://doi.org/10.51507/j.jams.2021.14.4.167. Acesso em: 20 mar 2024.
Abstract: Background: Electroacupuncture is one of the most popular physical treatments for clinical pain, but the potential influence of a patient’s age on the effectiveness of electroacupuncture treatment has not been clearly established. Objectives: The present study aimed to detect a potential difference in electroacupuncture- induced analgesia between juvenile and adult rats. Methods: In this study, we investigated the effects of electroacupuncture treatment on the nociceptive jaw-opening reflex evoked by tooth-pulp stimulation in juvenile and adult rats. Results: Our results showed there were age differences in electroacupuncture-induced analgesic effects in rats, especially with naloxone antagonization. The ratio of naloxonereversibility against electroacupuncture analgesia was greater in adult rats than in juvenile rats. Conclusion: These results suggest that electroacupuncture analgesia is produced mainly by the non-opioid system in juvenile rats and by the opioid system in adult rats.
metadata.dc.description.unidade: Faculdade UnB Ceilândia (FCE)
Colegiado de Bases Biológicas e da Saúde (FCE-BASES)
metadata.dc.description.ppg: Programa de Pós-Graduação em Ciências e Tecnologias em Saúde
Licença:: (CC BY NC) This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOI: https://doi.org/10.51507/j.jams.2021.14.4.167
Collection(s) :Artigos publicados em periódicos e afins

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