http://repositorio.unb.br/handle/10482/9587| Arquivo | Descrição | Tamanho | Formato | |
|---|---|---|---|---|
| ARTIGO_EnterolobinInducesRat.pdf | 149,47 kB | Adobe PDF | Visualizar/Abrir |
| Título: | Enterolobin induces rat paw oedema independently of PAF-Acether |
| Autor(es): | Faria Neto, Hugo Caire de Castro Cordeiro, Renato Sergio Balao Martins, Marco Aurélio Silva, A. C. V. Correira da Bozza, Patricia Torres Sousa, Marcelo Valle de Morhy, Lauro |
| Assunto: | Proteínas Edema |
| Data de publicação: | 1991 |
| Referência: | FARIA NETO, H. C. Castro et al. Enterolobin induces rat paw oedema independently of PAF-Acether. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 86, n. supl.II, p. 129-131, 1991.Disponível em: <http://www.scielo.br/pdf/mioc/v86s2/vol86(fsup2)_126-128.pdf>. Acesso em: 16 nov. 2011. |
| Resumo: | The potential participation of PAF-acether (PAF) on the paw oedema triggered by enterolobin was investigated. Intraplantar injections of enterolobin (5-20 µg/paw) yielded a dose response curve for oedema which appeared after 30 min, peaked in the interval between 2-4 h and faded after 24 h. The pre-treatment with BN 52021, but not with other PAF antagonists such as PCA 4248 or WEB 2086, significantly blocked enterolobin-induced oedema. To clarify better the discrepant results obtained with the PAF antagonists, desensitization to PAF was perfomed. The oedema triggered by enterolobin was not modified in PAF desensitized animals. It was concluded that the paw inflammation induced by enterolobin does not require PAF mechanism. |
| Licença: | "Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons (Attribution-NonCommercial 3.0 Unported (CC BY-NC 3.0). Fonte: http://www.scielo.br/scielo.php?script=sci_serial&pid=0074-0276&nrm=iso&rep=&lng=pt. Acesso em: 16 nov. 2011. |
| Aparece nas coleções: | Artigos publicados em periódicos e afins |
Este item está licenciada sob uma Licença Creative Commons
